I came across this verse the other day, in my devotions, and was comforted by the concept of God being over the impossible. As missionary appointees to Japan, sometimes it seems like we are attempting to do the impossible. Things like, trying to raise the required amount of funding for a family of seven, in a down economy. Trying to learn, as a family, the difficult Japanese language. And trying to present the gospel of Christ, to a people whose culture and society present obstacles and challenges to that work. But this verse gives hope.
Consider some of the impossibilities that had suddenly become possible in Luke chapter one: Zacharias and Elizabeth were having their first child even though Elizabeth had been barren and both of them were "well advanced in years". The neat thing about this is that this appears to be a direct answer to the prayers of this couple (Lk. 1:13) and their desires coincided with the perfect will of the Father (Lk. 1:25, cp. v.14, 36). And of course, another seeming impossibility, is Mary conceiving in her womb, being a virgin, and carrying a Child. And not just any child, for this child was the Son of God. (Lk. 1:35).
Something else to note, is that these people were living righteous and upright lives. Their righteousness was a result of their faith (Lk. 1:6, 28). And they were submissive to God (Lk. 1:23-24, 38).
So let us: "hope in God..." (Psalm 42:5), "wait on the Lord..."(Psalm 37:34) and live for Him, trusting in His Son, Jesus Christ. And if the Lord wills we will see impossibilities removed from our lives, for His glory and honor.
